IGF-I deficient mice show reduced peripheral nerve conduction velocities and decreased axonal diameters and respond to exogenous IGF-I treatment

1999 ◽  
Vol 39 (1) ◽  
pp. 142-152 ◽  
Author(s):  
Wei-Qiang Gao ◽  
Natasha Shinsky ◽  
Gladys Ingle ◽  
Klaus Beck ◽  
Kathleen A. Elias ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Conduction ◽  
Conduction Velocities ◽  
Igf I ◽  
Deficient Mice

scholarly journals Abnormalities of Peripheral Nerve Conduction in Relation to Thiamine Status in Alcoholic Patients

1991 ◽  
Vol 18 (2) ◽  
pp. 126-128 ◽  
Author(s):  
Monique L. D'Amour ◽  
Julie Bruneau ◽  
Roger F. Butterworth
Keyword(s):  
Peripheral Neuropathy ◽  
Peripheral Nerve ◽  
Thiamine Deficiency ◽  
Nerve Conduction ◽  
Peroneal Nerve ◽  
Activation Assay ◽  
Conduction Velocities ◽  
Neurotoxic Effects ◽  
Voluntary Basis

ABSTRACT:Thiamine status was evaluated using the erythrocyte transketolase activation assay in 20 alcoholic patients admitted on a voluntary basis to a Detoxification Unit. Electromyographic evaluation revealed significant reductions of motor and sensory conduction velocities in the alcoholic group. 38% of alcoholic patients had at least one abnormal peripheral nerve conduction parameter. Findings were consistent with an axonal type of neuropathy. 30% of alcoholic patients showed significant erythrocyte transketolase activation deficits indicative of severe thiamine deficiency. In the case of peroneal nerve, reduced conduction velocities were negatively correlated with abnormal transketolase parameters. These findings are consistent with a contributory (but not exclusive) role of thiamine deficiency in the pathogenesis of alcoholic peripheral neuropathy. Deficiencies of other vitamins as well as direct neurotoxic effects of alcohol could also be involved in this phenomenon.

scholarly journals Effects of Styrene on Peripheral Nerve Conduction Velocities in Rats

1997 ◽  
Vol 39 (4) ◽  
pp. 319-324 ◽  
Author(s):  
Tadashi Yamamoto ◽  
Keiko Teramoto ◽  
Shun'ichi Horiguchi
Keyword(s):  
Peripheral Nerve ◽  
Nerve Conduction ◽  
Conduction Velocities

scholarly journals Effects of manganese on the nervous system in rats. I. Study on peripheral nerve conduction velocities and action potentials.

Sangyo Igaku ◽  
1990 ◽  
Vol 32 (2) ◽  
pp. 136-137
Author(s):  
Hiroshi MITSUTAKE ◽  
Keiko TERAMOTO ◽  
Shun'ichi HORIGUCHI ◽  
Tadashi YAMAMOTO
Keyword(s):  
Nervous System ◽  
Peripheral Nerve ◽  
Nerve Conduction ◽  
Action Potentials ◽  
Conduction Velocities

scholarly journals PERIPHERAL NERVE CONDUCTION VELOCITIES IN CHAIN-SAW OPERATORS

Sangyo Igaku ◽  
1976 ◽  
Vol 18 (6) ◽  
pp. 516-520 ◽  
Author(s):  
Shunichi ARAKI ◽  
Tetsuo HONMA ◽  
Kazuo AOYAMA
Keyword(s):  
Peripheral Nerve ◽  
Nerve Conduction ◽  
Conduction Velocities

scholarly journals IGF-I expression is decreased in LIF-deficient mice after peripheral nerve injury

Neuroreport ◽  
2000 ◽  
Vol 11 (6) ◽  
pp. 1365-1368 ◽  
Author(s):  
Flora de Pablo ◽  
Lisa R. Banner ◽  
Paul H. Patterson
Keyword(s):  
Peripheral Nerve ◽  
Nerve Injury ◽  
Peripheral Nerve Injury ◽  
Igf I ◽  
Deficient Mice
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